ea0019oc24 | Cardiovascular metabolism | SFEBES2009
Agarwal N
, Rice S
, Bolusani H
, Newcombe R
, Ludgate M
, Rees A
Background: PCOS is a metabolic disorder associated with long-term health risks including insulin resistance, type 2 diabetes and dyslipidaemia. Metformin improves insulin sensitivity in PCOS and reduces circulating concentrations of markers of endothelial dysfunction, although it is unclear whether this translates into improvements in vascular function.Objective: To determine whether metformin therapy improves arterial stiffness and endothelial function...